diff --git a/INSTALL.md b/INSTALL.md
new file mode 100644
index 0000000000000000000000000000000000000000..b4a477df612e68cf64c624818ad049fbd609f7be
--- /dev/null
+++ b/INSTALL.md
@@ -0,0 +1,22 @@
+# INSTALL
+## Docker
+Install first [Docker](https://docs.docker.com/get-docker/)
+
+Then, run: `docker build -t 3dna .`
+
+## Conda
+Install first [Miniconda](https://docs.conda.io/en/latest/miniconda.html).
+
+Then, run: `conda env create -f environment.yml`
+
+# RUN
+## Docker
+`docker run --rm -v $PWD:$PWD -w $PWD 3dna python Main.py`
+
+## Conda
+`conda run -n 3dna python Main.py`
+
+or
+```
+conda activate 3dna
+python Main.py